Publications

Refereed Journal Articles since 2005

ML James, RR Fulton, J Vercoullie, DJ Henderson, L Garreau, S Chalon, F Dolle, S Selleri, D Guilloteau, M Kassiou. DPA-714, a new translocator protein (18kDa) (TSPO) ligand: Synthesis, radio-fluorination and pharmacological characterization. J. Nucl. Med (2008) in press.

A Van Dijk , C Johnston , HN Allbutt, M Kassiou, JM Henderson. Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions. Behav. Brain Res. (2008) in press.

L Besret, F Dollé, A-S Hérard, M Guillermier, C Coulon, M Ottaviani, M Bottlaender, P Hantraye, M Kassiou, Dopamine D1 receptors imaging in the rodent and primate brain using (+)-[11C]A-69024 and positron emission tomography. J Pharm Sci (2008) In press.

S Naidoo-Variawa, AJ Hey-Cunningham, W Lehnert, PL Kench, M Kassiou, R Banati, MR Meikle, High resolution imaging of the large non-human primate brain using microPET: A feasibility study, Phys. Med. Biol. 52 6627-6638 (2007).

P Emond, S Mavel, Y Zea-Ponce, M Kassiou, L Garreau, S Bodard, ML Marie-Laure Drossard, S Chalon, D Guilloteau, (E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter. Nucl. Med. Biol. 34 967-971 (2007).

N Giboureau, P Emond, R Fulton, D Henderson, S Chalon, L Garreau, P Roselt, S Eberl, S Mavel, S Bodard, M Fulham, D Guilloteau, M Kassiou, Ex vivo & in vivo evaluation of (2R, 3R)-5-[18F]-fluoroethoxy- & fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter, Synapse 61 962-969 (2007).

A Cagnin, M Kassiou, S Miekle, R Banati, Positron emission tomography imaging of neuroinflammation, Neurotherapeutics 4 443-52 (2007).

H Gunosewoyo, MJ Coster, M Kassiou, Molecular probes for P2X7 receptor studies, Curr. Med. Chem. 14 1505-1523 (2007).

H Boutin, F Chauveau, C Thominiaux, B Kuhnast, MC Gregoire, M James, S Jan, V Brulon, Y Fontyn, S Selleri, R Trebossen, P Hantraye, F Dolle, B Tavitian, M Kassiou, [11C]DPA-713:a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation, J. Nucl. Med. 48 573 - 581 (2007).

M Quinlivan, S Chalon, J Vergote, J Henderson, A Katsifis, M Kassiou, D Guilloteau, Decreased vesicular acetylcholine transporter and α4β2 nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning, Neurosci Lett 415 97-101. (2007).

RN Waterhouse, TL Collier, M Kassiou, Imaging sigma receptors: Applications in drug development, Curr. Pharm. Design 13 51-72 (2007).

AP Kozikowski, SK Chellappan, D Henderson, R Fulton, N Giboureau, Y Xiao, ZL Wei, D Guilloteau, P Emond, F Dolle, KJ Kellar, M Kassiou, Novel acetylenic pyridines for use in PET imaging of nicotinic receptors, ChemMedChem. 2 54-57 (2007).

X Liu, SD Banister, MJ Christie, R Banati, S Meikle, MJ Coster, M Kassiou, Trishomocubanes: Novel Sigma ligands modulate cocaine-induced behavioural effects, Eur J Pharmacol 555 37-42 (2007).

SD Banister, JK Clegg, MJ Coster, KA Jolliffe, M Kassiou, (1R,2S,3R,6S,7R,8S)-Tricyclo[6.2.1.02,7]-undeca-4,9-diene-3,6-diol. Acta Cryst. 63, 92-93 (2007).

James, Selleri, Kassiou, Development of Ligands for the Peripheral Benzodiazepine Receptor, Curr. Med. Chem. 3 1991-2001 (2006).

Cagnin, Kassiou, Meikle, Banati Clinical evidences of microglial activation in neurodegenerative dementia. Acta. Neurologic Scand 114 107-114 (2006).

Assard, Mavel, Parsons, Kruse, Galineau, Allouchi, Kassiou, Chalon, Guilloteau, Emond, Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands, Bioorg. Med.Chem. Lett. 16 2654-2657 (2006).

Thominiaux, Dollé, James, Bramoullé, Boutin, Besret, Grégoire, Valette, Bottlaender, Tavitian, Hantraye, Kassiou, Improved synthesis of the Peripheral Benzodiazepine Receptor Ligand [11C]DPA-713 using [11C]Methyl triflate, Appl. Rad. Isotop. 64 570-573 (2006).

F Issa, M Kassiou, HK Chan, MD McLeod, Synthesis and radiolabelling of ipratropium and tiotropium as PET ligands for the study of inhaled drug deposition, Aust. J. Chem. 56 53-58 (2006).

L Truong, H Allbutt, M Kassiou, JM Henderson, Developing a preclinical model of Parkinson's disease: A study of behaviour in rats with graded 6-OHDA lesions, Behav. Brain Res. 169 1-9 (2006).

J Vercouillie, S Mavel, L Galineau, T Ragusa, R Innis, M Kassiou, S Chalon, F Dollé, J-C Besnard, D Guilloteau, P Emond, Synthesis and in vitro evaluation of novel diphenylsulfide derivatives as serotonin transporter ligands, Bioorg. Med.Chem. Lett. 16 1297-1300 (2006).

C Thominiaux, B Bruin, Y Bramoulle, F Hinnen, S Demphel, M Bottlaender, L Besret, M Kassiou, F Dolle, Radiosynthesis of (E)-N-(2-[11C]methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor ligand, Appl. Rad. Isotop. 64 348-354 (2006).

A Mohamed, S Eberl, MJ Fulham, M Kassiou, A Zaman, D Henderson, S Beveridge, C Constable, SK Lo, Sequential 123I-Iododexitimide (IDEX) Scans in Temporal Lobe Epilepsy: A comparison to Neuroimaging Scans (MR and 18F-fluorodeoxyglucose (FDG) PET imaging), Eur. J. Nuc. Med. 32 180-185 (2005).

M Kassiou, SR Meikle, RB Banati, Ligands for the peripheral benzodiazepine binding sites in glial cells, Brain Res. Rev. 48 207-210 (2005).

SR Meikle, P Kench, M Kassiou, RB Banati, Small animal SPECT and its place in the matrix of molecular imaging technologies, Phys. Med. Biol. 50 R45-R61 (2005).

Y Zea-Ponce, S Mavel, T Assaad, P Emond, S Chalon, S Kruse, SM Parsons, N Giboureau, M Kassiou, D Guilloteau. Synthesis and in vitro valuation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter. Bioorg. Med. Chem. 13, 745-753 (2005).

X Liu, F Mattner, A Katsifis, MJ Christie, M Kassiou, Influence of trishomocubanes on sigma receptor binding of N-(1-benzyl-piperidin-4-yl)-4-[123I]iodobenzamide in vivo in the rat brain, Med. Chem. 1 31-38 (2005).

M Kassiou, RF Dannals, X Liu, DF Wong, RT Ravert, UA Scheffel, Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors, Bioorg. Med. Chem. 13 3623-3626 (2005).

ML James, RR Fulton, DJ Henderson, S Eberl, SR Meikle, S Thomson, RD Allan, F Dolle, MJ Fulham, M Kassiou, Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand, Bioorg. Med. Chem. 13 6188-6194 (2005).